C2Bio

Curated weekly digest of notable AI/ML and biotech developments. Flagged items are manually selected; remaining items are the week's most recent. 🧬 Biotech ★ Roche pens $2.5 billion pact for Hanmi's muscle-conserving obesity drug — Roche has entered a $2.5 billion deal to license Hanmi's early-stage muscle-conserving obesity asset, betting on a novel approach to weight loss that preserves muscle mass. (morning-news-biotech, 2026-08-26) ★ CRISPR Therapeutics reports Durability of Effects of CTX310 gene therapy at ESC Congress — CRISPR Therapeutics presented late-breaking abstract on CTX310, a CRISPR-Cas9 gene therapy targeting ANGPTL3 for familial hypercholesterolemia, with clinical update planned for August. (morning-news-biotech, 2026-08-26) ★ Ultrafast and reference-free sequence discovery in single-cell data — Abstract Knowledge of RNA sequences, expression, splicing, isoforms, structure and modifications is central for understanding and targeting cellu...

Curated weekly digest of notable AI/ML and biotech developments. Flagged items are manually selected; remaining items are the week's most recent. 🧬 Biotech ★ Human genetics across levels of biological organization — Genetic variation influences human physiology across biological scales from molecules to cells, tissues, organs and the whole organism. ★ From static structures to dynamic landscapes: cryo-EM redefines RNA biology — Recent advances in cryoEM are now transforming this landscape by enabling the visualization of RNA molecules across a broad spectrum of functionally relevant conformations at near atomic resolution (arxiv-digest, 2026-09-01) ★ Operationalizing open-ended biological discovery across single-cell representations — Projection into unseen datasets then evaluates their generalizability and phenotype association, providing a scalable screen for candidates that warrant prospective validation (arxiv-digest, 2026-09-01) ★ Learning Task-Specific Anti...